Selain Vino G Bastian dan Laudya Chintya Bella, film Buya Hamka juga dibintangi Desy Ratnasari, Donny Damara, Reza Rahadian, Ayu Laksmi, Anjasmara, Marthino Lio, Reybong, Mawar De Jongh, Mathias Muchus Verdi Solaiman, Teuku Rifnu Wikana, Ben Kasyafani, Wafda Lubis, Ferry Salim, Donny Kesuma, Cok Simbara, Roy Sungkono, Yoriko Angeline, Ajil Ditto, Zayyan Sakha, dan Yoga Pratama.***